Expression of clusterin in human renal diseases
نویسندگان
چکیده
منابع مشابه
Loss of Clusterin Expression Worsens Renal Ischemia Reperfusion
23 24 Prevention of ischemia-reperfusion injury (IRI) is a challenge in clinical care of the 25 patients with kidney transplants or acute kidney injury, and understanding of the intrinsic 26 mechanisms of resistance to injury in the kidney will lead to a novel therapy. Clusterin, a 27 secreted glycoprotein, is an anti-apoptotic protein in cancer cells. Our study is to 28 investigate the role of...
متن کاملIn Vitro Effect of Cell Phone Radiation on Motility, DNA Fragmentation and Clusterin Gene Expression in Human Sperm
Background Use of cellular phones emitting radiofrequency electromagnetic field (RF-EMF) has been increased exponentially and become a part of everyday life. This study aimed to investigate the effects of in vitro RF-EMF exposure emitted from cellular phones on sperm motility index, sperm DNA fragmentation and seminal clusterin (CLU) gene expression. MaterialsAndMethods In this prospective stud...
متن کاملAB212. Clusterin expression and human testicular seminoma
Clusterin expression has a positive correlation with the occurrence and progression of various types of tumors from different genetic backgrounds. Cluster in overexpression may protect tumor cells from apoptosis and damage caused by autoimmunity or anti-tumor therapy. Using immunohistochemisty, one previous study showed that clusterin protein expression is down-regulated in human testicular sem...
متن کاملLoss of clusterin expression worsens renal ischemia-reperfusion injury.
Prevention of ischemia-reperfusion injury (IRI) is a challenge in clinical care of the patients with kidney transplants or acute kidney injury, and understanding of the intrinsic mechanisms of resistance to injury in the kidney will lead to a novel therapy. Clusterin, a secreted glycoprotein, is an antiapoptotic protein in cancer cells. Our study is to investigate the role of clusterin in renal...
متن کاملAB214. Downregulation of clusterin expression in human testicular seminoma
BACKGROUND Clusterin, a heterodimeric glycoprotein of approximately 80 kDa, exists extensively in human body fluids. The abnormal expression of clusterin is closely related to the occurrence, progression, and prognosis of tumors. Up to now, few studies have focused on clusterin in human testicular cancer. This study describes an extensive exploration of the presence and expression of clusterin ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1994
ISSN: 0085-2538
DOI: 10.1038/ki.1994.109